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Analysis of protein structures and functions help in understanding the exact relationships between the proteins and in identifying protein families and features (Gaeta 1997; Lengauer, 2002). The data obtained is organised in such a way so as to access the already existing information on proteins, in this case and develop tools and resources to analyse the data.
For analysis of complete genomes and to determine which gene families are present in the protein and which are not present, several techniques such as location of genes on the chromosomes, correlation with function or evolution, expansion of duplication of gene families, identification of missing enzymes, and presence or absence of biochemical pathways are considered. Large scale events that have affected evolution of organisms are also studied for genome analysis.
When genes or genomes are analysed with respect to functional data the techniques used are expression analysis, micro array data, mRNA concentration measurements, protein concentration measurements, proteomics, and covalent modifications. For analysis of gene and genomes from a functional perspective, comparative analyses of biochemical pathways are made along with deletion or mutant genotypes vs. phenotypes and identification of essential genes, or genes involved in specific processes in structure and functions of the organisms (Lengauer, 2002).
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