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Microtubules - Essay Example

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Author : vernicearmstron

Summary

The researcher of this essay aims to discuss the microtubules through using specific examples. This also tries to describe the structure and function of the accessory proteins, which interact with microtubules, that are class of fibrous proteins formed within a cell…

Extract of sample
Microtubules

This essay focuses on the discussion of the microtubules, that on the molecular level comprise of tubulin molecules, which in turn are a heterodimer comprising of globular polypeptides, alpha and beta tubulin which are closely related and tightly linked. Many cellular functions are controlled by these microtubules which essentially are mediated through polymerisation and depolymerisation, which are controlled by nucleotide GTP. Following synthesis, there are molecular rearrangements within these microtubules are stabilized with accessory proteins, which are specific for particular tubulin. In this assignment from different cellular examples, these interactions between the specific accessory proteins and the microtubule molecular structure will be examined in order to describe the structures and functions of these specific accessory proteins. It has been demonstrated in the essay, that within the cell, there is continuous modification of microtubules which is conferred through a process of binding to other proteins. These are known as microtubule associated proteins or accessory proteins. The two main roles that these microtubule-accessory protein complexes perform are stabilization of the microtubular molecular structure against disassembly and more importantly mediation of their interactions with other components of the cell. The most significant and ubiquitous protein associated are ATPases which transduce energy also known as microtubule motor proteins which induce a sliding between adjacent microtubules. ...
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